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Recombinant Proteins
Panlabs leverages a robust microbial expression systems (Pichia pastoris and E. coli) to establish a highly efficient platform for the development and large-scale production of bioactive recombinant proteins. We currently focus on three core product categories:
- Cytokines: IL-2, IL-4, IL-6, IL-15, IL-18, IL-21, etc., providing immune modulation and repair functions.
- Growth Factors: FGF2, EGF, VEGF165, hGH, IGF-1, etc., promoting cellular regeneration and skin elasticity.
- Structural Proteins: Fibronectin, collagen fragments, etc., supporting skin firmness and barrier repair.
ENZYMES
Panlabs integrates molecular biology techniques with protein engineering to establish an efficient and scalable enzyme development platform, delivering key enzyme solutions for industrial processes and a wide range of biotechnological applications. Our primary enzyme offerings include:
Industrial & Bioprocess Enzymes: Amylase, Lipase, Cutinase, Esterase, Nitrilase, Endonuclease, Glucose Oxidase, Catalase Proteases: SUMO protease, TEV protease
LactosomeTM (Lactobacillus-Derived EVs)
Lactosome™ is a bioactive ingredient independently developed by Panlabs and belongs to the class of extracellular vesicles (EVs). It consists of nanoscale vesicles naturally released from probiotic Lactobacillus spp., exhibiting excellent biocompatibility and stability. Lactosome™ functions as a mediator of intercellular communication and is involved in immune modulation, anti-inflammatory responses, tissue repair, and cellular regeneration. Compared with animal-derived exosomes, Lactosome™ offers advantages in source safety, animal-free composition, high production yield, and process stability, aligning with sustainable and green manufacturing principles. It is suitable for applications in food, nutraceuticals, and cosmetic formulations.
L-PDRN (Lactobacillus-Derived Polydeoxyribonucleotide)
L-PDRN is a bioactive polydeoxyribonucleotide (Polydeoxyribonucleotide, PDRN) ingredient independently developed by Panlabs. It is derived from probiotic Lactobacillus spp. and composed of high-purity, low-molecular-weight short DNA fragments. PDRN is known for its excellent biocompatibility and tissue regeneration potential. Studies indicate that PDRN can activate cellular repair signaling pathways through stimulation of the adenosine A2A receptor, modulate inflammatory responses by suppressing pro-inflammatory cytokines such as TNF-α, IL-6, and IL-8, and promote the expression of VEGF and other growth factors, thereby accelerating cell migration, angiogenesis, and tissue repair processes.
Compared with conventional animal-derived PDRN, typically sourced from salmon sperm, L-PDRN is derived from Lactobacillus and features shorter DNA fragments (≤600 bp), enabling more efficient cellular uptake and enhanced regenerative efficacy. It also offers superior source safety, process stability, and scalability, while eliminating risks associated with animal-derived allergens and pathogens, making it suitable for applications in aesthetic medicine, biomedicine, and high-performance skincare.
L-PDRN (Lactobacillus-Derived Polydeoxyribonucleotide)
L‑PDRN is a next-generation, high-performance PDRN ingredient developed in-house by Panlabs, derived from Lactobacillus spp. It consists of short-chain Polydeoxyribonucleotide (DNA fragments) with lengths under 100 base pairs, featuring a simplified structure and high bioactivity. These short fragments are rapidly absorbed and utilized by cells, significantly enhancing tissue repair and regeneration efficiency.
Comparison Between L-PDRN and Conventional PDRN
| Item | L-PDRN (Lactobacillus-Derived) | PDRN (Salmon-Derived) |
| Source | Lactobacillus probiotics | Salmon sperm |
| Fragment Length | ≤600 bp, short fragments | Long fragments (200–800 bp) |
| Cellular Uptake | Highly efficient uptake and utilization | Relatively slow |
| Source Stability | Controllable process, high yield | Dependent on animal sources |
| Application Risks | Free from animal-related allergy and pathogen risks | Potential risks of animal-related allergies and pathogens |
Functional Pet Food-Fibi Cellulose Fiber Meat Paste
Fibi Cellulose Fiber Meat Paste is a functional pet food independently developed by Panlabs. Its key ingredient is microbially derived bacterial cellulose (Bacterial Cellulose, BC), characterized by high purity and a nanoscale structural architecture. Compared with plant-derived fibers, BC exhibits a finer structure and a unique three-dimensional network capable of efficiently adsorbing water and nutrients, providing a high surface area suitable for use as a prebiotic and nutrient carrier. In addition, its excellent water absorption and retention properties help improve stool quality, promote intestinal motility, and support overall gut health. Studies and practical applications further indicate that bacterial cellulose may help reduce intestinal inflammatory responses and assist in lipid regulation through binding cholesterol and bile salts.
