Fermentation Development

Fermentation Development
Provide optimal, robust and scalable fermentation processes

Panlabs has more than 35 years of experience in fermentation research and development, mainly focusing on the evaluation of fermentor culture of target strains, development and optimization of fermentation processes, and small-scale trial production. We have researched a wide range of microorganisms, including bacteria, yeasts, Actinomycetes and fungi. The team members of fermentation department are all experts with master's and doctor's degrees in related fields, with professional knowledge of microbial fermentation, combined with rich practical experience in fermentor culture. We provide customers with tailor-made fermentation development services, to meet the requirements quickly and effectively, and achieve the goal of commercial production.

On the construction of fermentors, Panlabs has built various sizes of fermentation tanks in our laboratory to meet the needs of different fermentation culture development. At present, the number of fermentors of each scale is as follows:

  • Size
  • Quantity
  • Brand
  • Remark
  • 1.2L x 8
  • 1
  • Biotop (Taiwan)
  • 1 vs 8 multiple parallel fermentor
  • 5L
  • 1
  • Major Science(Taiwan)
  • Airlift type
  • 6.5L
  • 2
  • Major Science(Taiwan)
  • -
  • 10L
  • 3
  • Able(Japan)
  • -
  • 30L
  • 9
  • B.Braun (Germany)
  • -
  • 140L
  • 2
  • B.Braun (Germany)
  • -
Fermentation Development Fermentation Development Fermentation Development

The main purpose of Panlabs’ fermentation R&D is to apply the improved strains in a practical industrial fermentation production. In terms of strain evaluation, we screen improved strains suitable for production in fermenters; in terms of process optimization, we explore the complete fermentation process including pre-culture conditions, media composition, main culture conditions and feeding strategy; in terms of scale up, Panlabs typically use 30L fermentors for validation, whose fermentation conditions can be suitably applied to pilot production. We also work with subcontracted fermentation companies to adjust materials and fermentation conditions to ensure that the plant can produce the desired product directly, quickly and consistently.

In addition, Panlabs is well-known for its excellent technical service, and we are fully committed to assist the customers in their scale-up development. Whether in our partner fermentation plants or in the production plants designated by our customers, we can provide timely explanations and responses in various ways, and offer comprehensive assistance to our customers to facilitate the scale-up production.

Example 1
Shake flask titer vs. 30L tank titer

Lipopeptide Produced By Fungi

Example 1
Example 2
Cyclopetide, Fungi
Example 2
Example 3
Streptomyces alkaloid
Example 3
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