Semisynthesis

Although some compounds could be obtained by complex chemical synthesis, the recovery rate and cost are not effective. Panlabs uses fermentation and enzymatic conversion method to produce intermediates of target compounds and obtain products with high purity and high recovery rate by the following semi-chemical synthesis.

Chemical synthesis needs a series of chemical reactions for the purpose of obtaining one or more products. It usually requires a multi-step reactions through physical and chemical methods, as well as multiple steps of purification to remove impurities.

The recovery or purity of the product is often unpredictable and requires the consumption of large amounts of organic solvents.

Panlabs uses microbial fermentation to obtain the precursors or intermediates of the target products first and then cooperates with the third parties to convert the precursors or intermediates into drugs or APIs by chemical synthesis (e.g., ADC warhead)
In addition to providing process improvement on a gram scale, we also guide customers to scale up production and process optimization.

The advantage of semi-synthesis could be:

Less chemical synthesis steps

Less solvent used

Reduce problems of low recovery rate and impurity

Cost effective

our equipment